V Montazeri, F Jafarpour Sadegh , S Hosseinpour, Hr Mirzaei, E Akbari, M Ehsani, S Akbari, N Asadi, M Mahmoudinezhad, E Mirtaheri, Z Sanaat, S Pirouzpanah,
Volume 12, Issue 1 (6-2016)
Abstract
Background and Objectives: Reproductive factors are in close relationship with breast carcinogenesis. This matched case-control study was conducted to study the association of reproductive risk factors with the risk of breast cancer (BC) among women in Tehran and northwest of Iran.
Methods: This hospital-based case-control study was performed on a total of 432 patients diagnosed with BC with confirmed histopathology who were recruited from hospitals affiliated with Shahid Beheshti and Tabriz University of Medical Sciences between 2007 and 2012, and 543 regionally matched controls without a prior history of BC.
Results: The average number of pregnancy and breast-fed children were significantly higher in cases than controls (P<0.01). The duration of breast-feeding was longer in patients (18.0±8.4 months) than controls (16.0±9.1; P<0.001). Most of the patients were diagnosed with BC above the age of 48 years old which was higher than the mean age of the recruited matched controls. Older age was associated with a 3.87 higher risks of BC development (95% CI: 2.94-5.10). The higher frequency of lactation in patients was significantly associated with the elevated risk (OR=2.22, 95% CI 1.62-3.04). The duration of breast-feeding within14-24 months was correlated with OR=0.52 to protect BC development during the reproductive age
(<48 years) (95% CI: 0.32-0.86).
Conclusion: High frequency of pregnancy, lactation, and older ages at first pregnancy are associated with the risk of BC, while older age at puberty, menopause, and longer duration of breast-feeding (age above 48 years) have inverse associations with the risk of BC.
M Pourranjbar, H Jamalizadeh, M Mehrtash, K Divsalar,
Volume 15, Issue 2 (9-2019)
Abstract
Background and Objectives: Menopause is one of the most sensitive events in a woman's life. Health improvement in this period can bring women a better quality of life and has many effects. This study was conducted to investigate the relationship between the level of physical activity and the level of health of postmenopausal women in Kerman Province.
Methods: A total of 536 postmenopausal women were selected from Kerman province. The Goldberg’s General Health Questionnaire was used to measure the level of health and the general physical activity questionnaire (GPAQ) was applied to determine the amount of physical activity. The formula for measuring body mass index was used for BMI. Ultimately, the Spearman, Kruskal Wallis, and Bonferroni statistics were used because the data distribution was not normal.
Results: The amount of physical activity in postmenopausal women in Kerman Province was lower than the WHO recommended. There was a significant relationship between physical activity with the level of health (r = 259), (P≤0.001). Moreover, BMI and health level had an inverse relationship (-0.186) (P≤0.001).
Conclusion: Based on the results, a significant relationship was found between physical activity and general health status of postmenopausal women. Considering the effect of physical activity on health, it can be concluded that increased physical activity of postmenopausal women in Kerman Province can improve their health and BMI.
