Volume 21, Issue 1 (Vol.21, No.1, Spring 2025)
irje 2025, 21(1): 23-35 |
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Fakhri-Demeshghieh A, Akbarein H, Bashar R, Shirzadi M R, Boluki Z, Ghasemzadeh N. Trend Analysis of Economic Losses due to Anti-Rabies Serum and Vaccine Consumption in Iran (2015-2022). irje 2025; 21 (1) :23-35
URL: http://irje.tums.ac.ir/article-1-7440-en.html
URL: http://irje.tums.ac.ir/article-1-7440-en.html
Aliasghar Fakhri-Demeshghieh1 
, Hesameddin Akbarein *2 , Rouzbeh Bashar3 , Mohammad Reza Shirzadi4 , Zahra Boluki5 , Narges Ghasemzadeh4
, Hesameddin Akbarein *2 , Rouzbeh Bashar3 , Mohammad Reza Shirzadi4 , Zahra Boluki5 , Narges Ghasemzadeh4
1- DVM, Specialty Board-Certified in Epidemiology, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
2- Assistant Professor of Epidemiology, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran ,akbarein@ut.ac.ir
3- WHO Collaborating Center for Reference and Research on Rabies, Pasteur Institute of Iran, Tehran, Iran
4- Center for Communicable Diseases Management, Ministry of Health and Medical Education, Tehran, Iran
5- Postdoc Researcher, Knowledge Utilization Research Center (KURC), Tehran University of Medical Sciences, Tehran, Iran
2- Assistant Professor of Epidemiology, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran ,
3- WHO Collaborating Center for Reference and Research on Rabies, Pasteur Institute of Iran, Tehran, Iran
4- Center for Communicable Diseases Management, Ministry of Health and Medical Education, Tehran, Iran
5- Postdoc Researcher, Knowledge Utilization Research Center (KURC), Tehran University of Medical Sciences, Tehran, Iran
Abstract: (696 Views)
Background and Objectives: Rabies is a public health threat worldwide. This study aimed to determine the amount and trend of the costs of anti-rabies serum and rabies vaccine in Iran between 2015 and 2022.
Methods: Using national data from March 2015 to March 2022, the cost of anti-rabies serum, human rabies vaccine, and the total cost of both were determined. The annual trend of the serum, vaccine, and total cost was determined using Joinpoint regression with a maximum of one.
Results: The highest rabies serum and vaccine costs were observed in 2021 and 2020 (58.3 and 6.874 US million dollars), respectively. Average Annual Percent Change was statistically significant (p<0.001) and indicated an increasing trend in the costs of anti-rabies serum. The trend in vaccine costs between 2015 and 2020 was increasing, and the annual percent change between 2015 and 2020 (p˂0.001) and 2021 (p˂0.001) were statistically significant. The average annual percentage change was statistically significant for the total costs of anti-rabies serum and rabies vaccine (p˂0.001) and indicated an increasing trend in Iran.
Conclusion: The lowest rabies vaccine costs were observed in 2021, which might be due to the COVID-19 pandemic. To reduce rabies losses, the domestic production of anti-rabies serum, implementing rabies control measures in unowned dogs, and increasing public awareness about animal bites, particularly dog bites, are recommended.
Methods: Using national data from March 2015 to March 2022, the cost of anti-rabies serum, human rabies vaccine, and the total cost of both were determined. The annual trend of the serum, vaccine, and total cost was determined using Joinpoint regression with a maximum of one.
Results: The highest rabies serum and vaccine costs were observed in 2021 and 2020 (58.3 and 6.874 US million dollars), respectively. Average Annual Percent Change was statistically significant (p<0.001) and indicated an increasing trend in the costs of anti-rabies serum. The trend in vaccine costs between 2015 and 2020 was increasing, and the annual percent change between 2015 and 2020 (p˂0.001) and 2021 (p˂0.001) were statistically significant. The average annual percentage change was statistically significant for the total costs of anti-rabies serum and rabies vaccine (p˂0.001) and indicated an increasing trend in Iran.
Conclusion: The lowest rabies vaccine costs were observed in 2021, which might be due to the COVID-19 pandemic. To reduce rabies losses, the domestic production of anti-rabies serum, implementing rabies control measures in unowned dogs, and increasing public awareness about animal bites, particularly dog bites, are recommended.
Type of Study: Research |
Subject:
Epidemiology
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